Rules like Lasting and Permanent injuries, and Severe Bleeding from Martial Arts still apply if used in the campaign. A major wound gives -5 to the knockdown check. Vitals (-3): Normal wounding modifiers (as torso). The vitals apparently include the lungs, kidneys, and liver as well as to the heart according to the Basic Set but a hit to the these former 3 organs is not even in the same league as a hit to the heart. This makes them extremely attractive and a single hit to the vitals can end a fight rapidly. They have no innate DR but a 3x wounding modifier and are only -3 to hit.
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